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Things to avoid while using Demerol Alcohol can interact with Demerol and increase the risk of certain side effects; please avoid it. It can impair your thought process. and make you feel dizzy or drowsy. Please be careful while driving, operating machinery, and performing activities that require you to alert and attentive. Consuming herbal products, vitamins, nutritional supplements, and other over-the-counter medicines while using Demerol might not be safe. What to do if an overdose happens? Demerol can adversely affect you if taken in excess. It can cause you the following overdose symptoms: • Slow or shallow breathing • Slow heart rate • Drowsiness or dizziness • Muscle weakness • Cold and clammy skin • blue-colored skin or lips • Fainting or unconsciousness • Coma You should consult your doctor ASAP if an overdose happens. You can also seek emergency medical assistance by calling the Poison helpline at 1-800-222-1222.